R-CHOP-14 is a chemotherapy regimen given to CD20 positive non-Hodgkin’s lymphoma. ‘R’ stands for the drug ‘Rituximab’ which is a drug targeted against the CD20 receptor on the lymphoma cells. ‘CHOP’ stands for the chemotherapy drugs ‘cyclophosphamide, doxorubicin, vincristine and prednisone.’ G-CSF is also given to keep the white blood cells at a safe level during treatment.